Orthomoleculaire suppletie tegen insulineresistentie
12 Apr, 2017
Door: Selma Timmer
Insulineresistentie speelt een centrale rol in de pathofysiologie van het Metabool Syndroom (MetS) en diabetes type 2. Verschillende voedingsstoffen en antioxidanten verbeteren de insulinegevoeligheid en kunnen als voedingssupplement worden ingezet bij de preventie en behandeling van MetS en diabetes type 2.
Insulineresistentie ontstaat en wordt versterkt door een aantal met elkaar samenhangende factoren, die een vicieuze cirkel vormen:
• Laaggradige ontsteking: een te veel aan vetweefsel, met name in de buikholte, produceert pro-inflammatoire cytokines en zorgt voor chronische laaggradige ontsteking, hetgeen de insulinesignalering verstoort.[4-6] Laaggradige ontsteking door andere oorzaken zoals veroudering van het immuunsysteem (inflamm-aging), hyperhomocysteïnemie, AGE-vorming (advanced glycation end products), chronische ontstekingsziekten, en intestinale disbiose met verhoging van de darmpermeabiliteit (bijvoorbeeld door stress of overeten) bevordert eveneens insulineresistentie.
Lees het gehele artikel vanaf pagina 24 in OrthoFyto 2/17.
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